In today’s episode, Prof. Andrew Ewald, Director of the Cell Biology Department at the Johns Hopkins School of Medicine is interviewed by Inês Tomás. Prof Ewald explains how he transitionned from a background in physics to the field of cancer biology. He touches upon why cancer is such a specific type of disease, how cancer cells talk to each other during metastasis, and how their interaction with immune cells is crucial for disease development. Prof Ewald also discusses the evolution of the tools available for cancer biologists and how the emergence of new technologies are changing the field. Lastly, he shares some inspiring mentoring advice on how to reach an interdisciplinary and rewarding career.