Episode Transcript
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0:00
Welcome back to doctor Wendy Walls Show on KFI AM six forty were live everywhere
0:04
on the iHeartRadio app. You know, I get really excited when I have
0:07
a guest that has a bigger brain than me. I measured, actually his
0:10
like four inches in circumference, bigger than mine. He has more degrees than
0:14
you can imagine. I'm sure I would need a dictionary to translate some of
0:17
his research papers, but it's always a thrill. My next guest is doctor
0:22
Dave Rabin. He's not only an MD, is he? When they have
0:25
a whole bunch of letters after their names, you gotta let go. Whoa
0:28
not only a medical doctor, a PhD, A neuroscientist, a psychiatrist.
0:33
Yeah, that's like up above a psychologist because they can give you the med
0:36
stew He is co founder of something called Apollo Neuroscience. We're gonna talk about
0:43
later, but a lot of his research has to do with ketamine an MDA
0:51
m A assisted therapy with his patients. Basically, he's a leader in a
0:54
psychedelic field. Welcome doctor Rabin. How are you great? Thanks so much?
0:59
Tracking me on your brain is like bursting out your ears. You're too
1:03
kind of So, you know, ketamine has been in the news recently.
1:07
Sadly, a beloved celebrity who suffered with addiction most of his life, Matthew
1:11
Perry from Friends, passed away and when the toxicology results came out, they
1:17
said he had an overdose of ketamine. All right, First of all,
1:19
let's go to the beginning. What is a psychedelic drug? What is ketamine?
1:25
Is it something like having to do with magic mushrooms. That's a great
1:27
place to start. And I think one of the most common misunderstandings that we
1:30
have is about what the word psychedelic means, because it doesn't actually just refer
1:34
to drugs. It actually refers to a state of mind. And psyche means
1:40
mind from Latin Dellos means to show or to reveal. So what we're really
1:44
talking about is entering states of mind or states of conscious awareness where we're revealing
1:49
parts of ourselves to us that are effectively not necessarily noticeable, things that have
1:56
happened to us in the past, past memories, parts of ourselves that maybe
2:00
we don't like, that we shoved underneath the surface because people in our childhood
2:04
told us that those you know, weren't the best parts we should be showing
2:07
off. And so in us with the psychedelic drug like ketamine or MDMA or
2:15
psilocybin, which are in trials now, and ketamine is the only legal psychedelic
2:19
medicine we have available for depression. These medicines are molecular tools that help us
2:24
to basically quiet our survival ego mind for a short amount of time so that
2:30
we can bear witness to what lies underneath the surface of our consciousness, and
2:36
so it reduces our defenses and we're able to act propers are unconscious. You
2:42
know. I teach undergrads, and when I'm trying to explain the difference between
2:46
the conscious and unconscious, I show one of those classic pictures of the iceberg
2:51
with just the tip above the ocean and the giant iceberg underneath, and I
2:54
say, that's our conscious up there above. That's why we're aware of our
2:58
thoughts. We think we know everything. That's it. The rest is going
3:00
on below surface. I know lay people like to use the word subconscious,
3:06
but as fancy people, we use the word unconscious. In the unconscious is
3:12
really the big motivators for our behavior. So you're saying psychedelics help us look
3:15
underwater and see what's there exactly, And you nailed it with that metaphor.
3:20
I think it's one of the best metaphors for consciousness because when you and the
3:23
most important thing is you can access psychedelic states of mind. And we all
3:28
have accessed these states of mind without drugs. So the most common way is
3:31
in dreams. Right. We know that when we dream, we're starting to
3:36
experience things about ourselves and about the world that we don't necessarily notice when we're
3:39
awake. And part of that is because our ego, our defensive mind that's
3:45
awake and active all the time during the day, feels safe enough to relax
3:49
and calm down, and then we can become aware and start to notice things
3:53
going on beneath the surface. So if you think about what psychedelic medicines are
3:57
doing, and what deep breathing intention breathing states are doing, a meditation and
4:00
yoga, they're all bringing us access to the same states which are effectively psychedelic,
4:06
like dreams. And ketamine is really interesting because it's only sixty to ninety
4:11
minutes as a therapy, but it gives people access to a very when used
4:15
properly, a very comfortable, safe, dream like state where they can start
4:19
to self reflect non judgmentally on themselves. And when you've been judging yourself for
4:26
maybe days, weeks, months, decades, being able to observe yourself without
4:30
judgment could be one of the most therapeutic things you've experienced in your entire life.
4:33
And I want to add this about dreams. My belief system on dreams
4:36
is that they're never literal folks. They're always metaphors. And everything in the
4:41
dream, whether it's the chair, the cigarette, you, the person they're
4:44
talking to you, is a piece of you. So I always ask you, like, well, if you were the chair, what would you think
4:49
of that? You know, if you are the other person you were talking
4:51
to, what you think? And that's one of the ways to access some
4:55
good what did Freid call it? The Royal Road to the unconscious dream material?
5:00
I years ago, when I was in psychotherapy psychoanalysis had EMDR. Look.
5:05
I opened my hands like this when I said, at EMDR, it
5:09
feels like it's opening a circuit board. And for those who don't know what
5:12
does EMDR stand for, it's I have to think eye movement disensitation in an
5:18
r and rabbit. I was something, and so the clinician just takes their
5:24
finger and goes back and forth, and you just watch it back and forth
5:27
like a tennis match with your eyes, and it somehow relaxes your consciousness and
5:30
you're able to access early memories. I actually, in EMDR remembered in a
5:34
non traumatic way some abuse by a dentist when I was six. And the
5:39
way I described the memory afterwards is I said to her, you know,
5:44
it feels like you know when you leave a restaurant and you go, oh my god, I forgot my purse and you run back real quick because it's
5:48
something important, but you just ran back to get it. The world wasn't
5:53
ending, just oh my god, I forgot my purse. That was Oh
5:55
my god, I forgot that memory, And there it is. So let's
5:59
talk about uses of you said, ketamine is the only legal psychedelic drug at
6:02
this point. What is it mostly prescribe for? So ketamine is only FDA
6:09
cleared at this point for treatment resistant depression, but it's used off label for
6:13
PTSD, and early studies have shown that is also effective when used properly for
6:17
certain anxiety disorders. Social anxiety disorders. So it has because the modern theory
6:25
of psychology and psychiatry around mental health is that most mental illnesses seem to stem
6:30
from one or multiple past traumatic or negative threatening experiences that we've had that have
6:36
shaped the way we see ourselves in the world. That we might have buried
6:40
deep down beneath the surface of the water in that iceberg metaphor right deep iceberg
6:46
part that might be and probably is maybe one hundred million times as big as
6:49
the part that's sticking up out of the surface. Then ketamine therapy in the
6:55
context of having therapists a therapist or two with you who understand how to help
6:59
provide this effectively safe space for you to bring up whatever comes up so that
7:04
you don't resist it, right, because if you were feeling and you have
7:08
the training, so when that memory came up for you, you have the
7:12
training to kind of address it and allow it and process it. But for
7:17
people who have those kinds of memories come up in an unsafe environment terrifying,
7:21
it's terrifying. It can be almost like reliving a nightmare, right or the
7:26
or the traumatic experience itself. And so the main caveat of psychedelic medicines.
7:30
The two main caveasts are number one, they're not for everyone, and number
7:34
two they are they need to be administered in the proper safe setting. Yeah,
7:40
you don't go home and do this. This is something in a clinical
7:43
setting with somebody observing and helping you through the situation. All right, when
7:46
we come back, we have to go to break. I want to talk a little bit about Matthew Perry, what little you may know about his situation,
7:53
because everybody wants to know inquiring minds, and also I know this is
7:57
a separate subject, but you know it's about a care about You have a
8:01
device actually that helps improve orgasms in women. Oh you guys, you got
8:07
to stay for this. You won't believe it. My guest, doctor Dave
8:11
Rabin, a medical doctor, psychiatrist, neuroscientist, one of the leaders in
8:15
psychedelic medicine. Doctor Rabin, can we talk a little bit about Matthew Perry's
8:20
death? Heartbreaking? They say it was because of Ketymine. I thought Ketymine
8:24
was safe. Yeah, it's a great question, and you know, I
8:28
think that it goes without saying that Matthew Perry's death was an absolute tragedy and
8:33
that as a medical community, we probably could have done a better job helping
8:37
him manage his addiction. Addiction itself is one of the most challenging mental illnesses
8:43
to manage today, and interestingly, psychedelic medicines used properly as we were talking
8:48
about earlier in the safe environment, are one of the best treatments that we
8:52
have for addiction. Now that is coming down the clinical trials pipeline. But
8:56
I think the main point to make here is that mean is actually one of
9:01
the safest met psychedelic medicines and the safest medicines for depression with the lowest risk
9:05
of side effects that we see across the board in depression treatment. So how
9:11
did he pass away from that? Because it has sedative properties, and ketamine
9:16
has actually been used for over seventy years, originally as an anesthetic agent to
9:20
prevent soldiers from going into shock when they're wounded in Vietnam. That's how it
9:26
originally started to be used. And it's used as a surgical anesthetic to reduce
9:30
pain and to help you don't get into hot tubs when you have an anesthetic.
9:33
Don't get into hot tubs with anything that sedates you or anything that's an
9:35
anesthetic and he had from what we can tell, probably some other low levels
9:39
of other medicines he was taking that were also slightly sedating on board. And
9:43
so you know, people can pass out in hot tubs without any drugs on
9:48
board, just by getting too hot. All of a sudden, you add
9:50
a sedative hypnotic medication or something that is slightly anesthetic in there, and you
9:56
got Whitney Houston, and you have a real problem. And I think that's
9:58
why we don't recommend in general, using any kind of sedative hypnotic drug when
10:03
you're in a hot tub, including alcohol, but also to have somebody with
10:07
you if you're taking any of those medicines and you happen to go into an
10:11
environment like that where you could pass out a sauna, a hot tub.
10:16
You know, most drownings unfortunately occur in three feet of water, right,
10:20
So we really need to be This is just a warning call, I think
10:22
to us to just be more careful and mindful about what we're putting into our
10:26
bodies when we're going into these seemingly benign situation. Yeah, I mentioned Whitney
10:31
Houston. I remember interviewing a doctor after her tragic death, and he looked
10:35
at the toxicology report and said there was a number of not only sedatives,
10:39
but respiratory depressants. And so even if you you know, for an average
10:43
person, if we happen to slide underwater, we have like an effect where
10:46
we are, you know, jerk and open up our mouths, and she
10:50
wouldn't have had the right that that tool available under those medications. So heartbreaking.
10:54
And one of the common side effects of ketamine that you know, we
10:56
always educate people on when they're using it under supervision is that ketamine, because
11:01
of the nature of its dissociate and anesthetic properties, it makes it a little
11:05
hard to move at peak doses. And that's why that's why people you know,
11:11
we make sure people are supervised when they're using it. But that's also
11:15
why it works great for surgery. So we want we always try to make
11:18
sure that people understand you may not be able to take care of yourself for
11:22
the next hour, so we need to be extra careful that during that hour
11:26
you're supervised, you're not doing anything potentially dangerous. And unfortunately Matthew Perry didn't
11:31
have that kind of supervision, and so you know, ketamine was unlikely to
11:35
be the cause of death, but the misuse of it might and likely contributed
11:41
to and probably with some of the other medications. Exactly, it's a combo.
11:45
Yeah, May he rest in peace. Now, I want to talk
11:48
a little bit about vibrations and our body. You know, one of the
11:52
things I teach in my health psychology class is it's interesting that while religion happens
11:58
to be in decline in an hour country, in western cultures, that religiosity
12:03
is highly correlated with better health and longer life. Well, partly because there
12:07
isn't a religion who preaches sex, drugs and rock and roll, so they
12:09
kind of clean living. But also the community benefits all kinds of things.
12:15
But there's also this chanting every religion in the world, whether you're going or
12:22
Hail Mary full of graziolad is with the you've got some kind of repetitive sound
12:26
that makes vibrations in your body. How does this relax somebody? So it's
12:31
a great question, and I think you know, religion. There's three important
12:35
things we can take away from religion. You mentioned all three of them just
12:39
now, right, So one of them is community. Right, part of
12:43
why religion is so beneficials because it helps bring us together. Number two,
12:46
it gives us something to believe in. It's greater than ourselves, hope.
12:50
Right. And we know from studies now of people who have had terminal illnesses
12:54
that if you believe in anything bigger than yourself, your chances of survival and
12:58
your experience of end of life is better quality of life wise. And number
13:03
three is the chanting and the vibrations and the singing, and all of that
13:09
comes together around what happens in our nervous system, which is it helps us
13:13
feel safe. Right. And this is going back to one of my favorite
13:18
topics and I think yours two, which is how we evolved as human beings
13:22
and animals is we evolve to keep each other and ourselves safe as a priority.
13:26
So if we feel threatened in our environment, our bodies don't function properly
13:31
because they take all of our available blood and resources and send it to heart,
13:33
lungs, skelet the muscles, motor cortex, fear center to get us
13:37
out of that threatening situation, to get to safety. And once we're in
13:41
safety, all of a sudden, we take all that blood and we send
13:45
it back to reproduction, digestion, immunity, metabolism, at sleep, rest,
13:50
and recovery, empathy, right, all the stuff that we want to
13:52
have active when we're not running from a lion. So training our bodies over
13:56
time with these three things. Belief, community, safety from other people around
14:01
us that we can trust and feel comfortable around. And vibration all help whether
14:07
you're singing it or whether you're feeling it through something like apollo or a hug
14:09
or a purring cat, all forms of healing. Vibration, they all help
14:15
to amplify safety pathways in the brain and body, which reduces stress and anxiety.
14:18
Now you mentioned the word Apollo. You have a company called Apollo that's
14:22
got a vibration device that someone can wear like on their wrists. They're opera
14:26
arm and what does it do? So we developed the Apollotechnology actually out of
14:31
my research into how psychedelic medicines work and when I was being when I was
14:37
training in psychedelic assisted therapy in over the last ten years, I was always
14:41
interested, why do these medicines plus therapy with just a few doses. We're
14:45
not talking daily dosing. We're talking, you know, three to twelve doses
14:50
over twenty weeks, right, so it's very few doses. And then there's
14:54
a break and people get better in the short term, and then they stay
14:56
better long term, even if they've never responded to any their treatments. So
15:01
to put it very clearly, some of the evidence that's coming out now around
15:05
MDMA assisted therapy, which is on the FDA's desk for clearance right now,
15:09
and with ketamine for depression, which is one of the only anti suicidal medications
15:13
we've ever discovered, incredible, right wow, and psilocybin for depression, which
15:16
is having similar benefits. These are showing in our trials some of the greatest
15:20
results in terms of outcomes that we've ever seen in the history of psychiatry.
15:24
But they also require you to take a psychedelic drug, which is not for
15:28
everyone, and that requires therapists to be there. I'm in control, freak,
15:31
I'm afraid of drugs, right, and lots of people are and lots
15:33
of people, boy, did I take de little vibrator out of your hand?
15:35
Test? Well, lots of people aren't good candidates for drugs too,
15:39
like many children, right and elderly folks. And so we thought, well,
15:43
if we can figure out the core pathways that are being activated by the
15:48
psychedelic therapy, maybe we can develop technology that activates those pathways on the go
15:52
for us and helps boost safety on the go. And so we figured out
15:56
in the University of Pittsburgh Department of Psychiatry that we could delivering vibrations to the
16:00
body that kind of feel like if you're familiar with holding a purring cat or
16:03
getting a hug, and that feeling, that feeling is something we can induce
16:07
for ourselves with breathing. And Apollo works by sending these soothing vibrations to the
16:11
body that induce that safe, natural, meditative breathing state on the go.
16:17
And so what is it? You wear it for how long? And it's
16:21
I mean, I'm holding it. It's a gentle vibration feeling. But how
16:23
does it actually work? So it works by you can wear it as long
16:27
as you want. It works anywhere in your body. It's a pod.
16:30
You can clip it onto your body. You can wear it through clothing or
16:33
overclothing. You can wear it on a strap. Most people wear it on
16:36
their chest or ankle or wrist, and you can wear it as long as
16:40
you want. It's basically music that you can't hear that your body is sensitive
16:44
to. That calms the body and helps you to just feel safe, in
16:48
control, clear and focused, so sleepy, Can you stay for one more
16:52
segment because I have a big question about is feeling safe always okay? Like
16:56
aren't we supposed to be scared to make some good decisions? And also I
17:00
promised you're going to hear how this can improve our relationships, especially for ladies.
17:04
My guest doctor Dave Raebin, a medical doctor, a psychiatrist, a
17:10
neuroscientist, PhD, more letters after his name than you could ever imagine,
17:15
basically someone you should trust. Earlier, you were telling us that you know
17:18
you have this device called Apollo. I should say where do people get this
17:22
Apollo thing? They can go online and do Apollo dot polloneuro dot com,
17:26
oh, Apollo neuro or wearablehugs dot com. Wearable hugs isn't that cute?
17:30
Dot com? And this is vibrating thing you can wear around. It puts
17:33
you in this state of relaxation, so you're not in a stress anxiety fear
17:36
state. My question is this didn't Mother Nature design some anxiety for a darn
17:41
good reason? And if we walk around too relaxed all the time, maybe
17:45
we're not making good decisions. That's absolutely true. And this is actually one
17:51
of the things that's most commonly not taught correctly, is that we did evolve
17:56
that system for a reason. But the evolutionary biology feel and Eric Candell,
18:00
who's also a famous psychiatrist and a neuroscientist who won the Nobel Prize in two
18:04
thousand, basically won it for discovering that there are only certain things we're supposed
18:11
to have our fear center fight or flight system turn on for. Oh,
18:15
and those are actual survival threats running from a lion, running from a lioner
18:19
predator, lack of food, lack of water, lack of air, and
18:23
lack of safe shelter. That's it. But all the interpersonal problems, don't
18:29
They all boil down to I'll be left alone in the jungle to die if
18:32
they all abandon me. And that's an assumption that we make that often increases
18:37
our chances of being left alone because then we act from a point of insecurity
18:41
rather than strength. And so when we act from insecurity, what do we
18:45
do we make more selfish decisions? Right? Wow, So that's called in
18:49
psychology, it's called misappropriation of threat, which simply put, is just interpreting
18:55
things as threatening when they're actually not right. And so that's what all these
18:59
meditations, soothing touch, soothing music, psychology, and psychotherapy techniques have all
19:03
focused on, is how do we teach people to understand the skills and practice
19:08
the skills of reminding ourselves that we're not under actual threat when we're not under
19:14
actual threat, so that we can allow our recovery system to do its thing
19:18
and keep us feeling good unless we're actually running from a lion. Because when
19:22
we're actually running from a lion, our bodies don't allow us to do anything
19:26
else. We are in that mode and we have to get out of there
19:30
before we can do anything else. And in today's time, we're not running
19:33
from lions. We are running from emails exactly, traffic, mud slides,
19:38
whatever it may be. You know, over Christmas, I was at a
19:41
Christmas party and I met a psychotherapist from Russia, and I saw, what's
19:45
the difference between what are the big issues in Russia compared to here? You
19:48
know, I love to find out And she said, well, first of
19:52
all, Russians think it's crazy that Americans always want to get rid of their
19:55
anxiety. Russians are like we need to be worried. We have anxiety,
19:59
we don't want to get rid of it. About how fascinating anyway, Let's
20:03
talk about relationships, love and how this Apollo device can even help your relationships.
20:11
So one of the biggest challenges that we face in feeling afraid or feeling
20:18
stressed is thinking, like you alluded to earlier, that we might not be
20:22
loved or we might not be accepted by our colleagues, our friends, our
20:26
peers, our families, and that can make us feel really unpleasant and uncomfortable
20:32
because we all as humans want to be loved, we want to be accepted,
20:36
we want to be connected to our community. It's fundamentally important, critical
20:41
for our healthy, happy survival, and for joy in our lives. And
20:45
we have huge parts of our brains that evolved, like the insolent cortex,
20:48
that are solely responsible for empathy and connecting with other human beings, and we
20:52
need to use those parts. So tools like Apollo we develop to try to
20:59
help re train us to remember how to use those parts of our brains again
21:03
through our sense of touch. And what's really interesting is that the two states
21:10
that are most vulnerable and therefore scary for us when we're not when we're feeling
21:15
stressed out, are sleep because sleep is when we're completely physically defenseless. So
21:19
we have to feel safe to get into deep and rem sleep states, which
21:22
is where we get all our physical and emotional mental recovery. And then sexual
21:27
and intimacy in relationships because oh, yeah, you've got to be relaxed.
21:32
You've got to be relaxed, and the room's got to be clean, Julio,
21:34
if you're listening, we need to clean the bedroom. Okay, it'll
21:37
work better. Yeah, Because you're really like allowing yourself to completely open up
21:44
and connect with another human being, and that's vulnerable. And especially if you're
21:48
a woman, you're you're often uh you know, and you're and you're interacting
21:52
and dating men. Right, men have more physical prowess, more strength,
21:56
meant there's a huge history of violence against women from men. We can't deny
22:00
it, right, that's just part of our unfortunate and unfortunate part of our
22:04
society, and that collective trauma exists. And so a lot of the tools
22:10
we use help around sex and intimacy and love and connection are really about just
22:15
helping women and men feel safe in their own bodies, and over the last
22:19
few years we figured out a way to do that for women for intimacy using
22:22
Apollo, which is really exciting. So Apollo has a separate setting, like
22:26
a vibe setting that increases intimacy for women. It does what's it called.
22:30
It's called the Love vibe, of course, and anybody who has the Apollo
22:33
app and the Smart Vibes sub brain of Apollo, which is where we the
22:40
Apollo as a device comes with eight eight vibes that you can select from which
22:45
allow you to access different states of anything from high energy and focus and socializing
22:49
to calm, relaxation, meditation. This is a special vibe that we released
22:55
to all of the subscription users that are members of Smart Vibes, which allows
23:00
people to access the more advanced and interesting states that we've discovered over the years,
23:03
and one of them is intimacy for women and helping women feel safe enough
23:07
in their own bodies to allow themselves to really connect with their partners physically,
23:12
mentally, emotionally. So would it be possible we can give one away to
23:17
a listener, of course, all right, listen to everybody next week. Next week, when I get one in my hot little hands, Cayla's going
23:22
to be taking your calls. We're going to open up the phone lines and
23:26
you can call in and win an Apollo device that has the Love Vibe on
23:33
it. It is always a pleasure to meet someone of your caliber, your
23:37
expertise, and you're well spoken, Doctor Rabin. Now where can people find
23:41
out more about you? Please come find me on my website at Apollo dot
23:47
Clinic or doctor Dave dot Io, and come find me on socials. I
23:49
love to hear from you and hear your thoughts. It's at doctor David Rabin
23:53
on Instagram and Twitter. You got doctor Dave dot Io. Look at that.
23:59
That's it. You are ol Man. Pleasure to meet you and thank
24:03
you for listening to The Doctor Wendy Wall Show.
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