Doctor John and Doctor Guy roll their wagon wheel along the Oregon Trail as they describe the dangers and maladies of the 2170 mile long journey as well as the unfortunate paucity of medical interventions available to the average traveler.  It was a magical place where Arrows, lightening strikes, mule kicks, and  a plethora of diseases awaited the weary settlers... all of whom were probably treated with enemas.  

Ox wanders off.  Loose 2 days.  Savannah has typhoid.  Tommy has dysentery.  Miss Tina has exhaustion.  (Personally, I never made it to Oregon)