In this lecture, you will learn about best practice guidelines informing the management of pain in the critically ill adult. The updated definition of pain, its prevalence and challenges in the adult population in the intensive care unit (ICU) are described. A stepwise approach to pain assessment in the patient unable to self-report is presented and various valid pain assessment tools are introduced along with new developments. Pain management guiding principles based on a multimodal analgesia approach are also discussed.

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