As the backlash grows, Purdue Pharma aggressively defends OxyContin, even amid evidence it’s being overprescribed and far more addictive than they indicated. Two ambitious federal prosecutors decide it’s time to bring criminal charges against Purdue. OxyContin sales begin to dip as more doctors and patients become aware of just how addictive it is. But the damage is done, and America finds itself in the throes of a full-scale epidemic of opioid addiction and abuse.

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